HomeNCAA PicksSouth Carolina VS Coastal Carolina Prediction: November 22, 2025

South Carolina VS Coastal Carolina Prediction: November 22, 2025

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South Carolina hosts Coastal Carolina on November 22, 2025, at Williams-Brice Stadium in Columbia, SC, with kickoff set for 4:15 PM EST. This NCAA matchup pits a struggling Gamecocks offense against a Chanticleers squad riding recent momentum. Defensive vulnerabilities on both sides could create a competitive spread scenario despite the home advantage.

South Carolina’s offensive woes, ranked 116th nationally with just 20.7 points per game, contrast sharply with Coastal Carolina’s strong rushing attack averaging nearly 194 yards on the ground. The spread sits at 23.5 points, and favorable weather conditions with 78°F and no precipitation should allow both teams to execute their game plans without environmental interference.

Early expectations favor the home side to win outright, but Coastal Carolina’s recent form and experienced core suggest they can keep this contest closer than the market anticipates. This South Carolina vs Coastal Carolina game preview examines whether the Gamecocks can cover or if the South Carolina vs Coastal Carolina betting odds overvalue home-field advantage against a resilient opponent.

Key Factors for South Carolina vs Coastal Carolina

South Carolina has dominated at home against non-ranked opponents, winning eight of its last nine such matchups at Williams-Brice Stadium. However, the Gamecocks enter with a 2-3 record in their last five games, revealing inconsistency. Meanwhile, Coastal Carolina has won four of its last five overall, showing superior recent momentum despite road struggles in November.

The Chanticleers’ ground game presents a legitimate challenge to South Carolina’s defensive vulnerabilities. Both teams are dealing with defensive issues, but Coastal Carolina’s 194 rushing yards per game could exploit the Gamecocks’ weak front. No major injuries or suspensions are reported for either side, ensuring both squads field their strongest available lineups in ideal 78°F conditions.

The South Carolina vs Coastal Carolina betting forecast must account for offensive limitations on the home side and road difficulties for the visitors. While South Carolina’s home dominance is notable, their offensive struggles at 116th nationally limit their ability to pull away. This dynamic makes the South Carolina vs Coastal Carolina prediction more nuanced than the spread suggests, favoring value on the underdog.

Recent Trends for South Carolina vs Coastal Carolina

Coastal Carolina’s four wins in five games contrast sharply with South Carolina’s 2-3 stretch, highlighting a clear momentum advantage for the visitors. However, the Chanticleers have lost four of their last five road games in November and failed to cover the spread in recent non-conference matchups, creating tension between overall form and specific situational performance.

South Carolina’s home success against non-AP teams provides a strong historical baseline, yet their offensive ranking of 116th nationally raises questions about their ability to build comfortable leads. Coastal Carolina’s experienced core and rushing prowess should help them control clock and limit possessions, making a close, competitive game the most likely outcome despite home-field advantage.

The South Carolina vs Coastal Carolina matchup trends reveal defensive issues on both sides and contrasting offensive identities. South Carolina struggles to score consistently while Coastal Carolina relies on a methodical ground attack. These South Carolina vs Coastal Carolina betting insights suggest the spread is inflated, with the visitors possessing the tools to stay within the number despite their November road woes.

Our Prediction is Coastal Carolina +23.5

Coastal Carolina +23.5 represents excellent value given their recent four-win stretch and South Carolina’s offensive limitations. The Gamecocks’ 20.7 points per game ranks 116th nationally, making it difficult to envision them covering a nearly four-touchdown spread. Coastal Carolina’s 194 rushing yards per game should keep drives alive and limit South Carolina’s offensive possessions effectively.

While South Carolina’s 8-1 home record against non-ranked teams is impressive, most of those victories likely came by narrower margins than 23.5 points. Both defenses are vulnerable, which typically produces closer games. No injury concerns and ideal weather conditions favor execution over randomness, allowing Coastal Carolina’s experienced core to perform at their ceiling on the road.

We believe the outcome of the match will be Coastal Carolina +23.5. The Chanticleers’ momentum and rushing attack provide the foundation to stay competitive, while South Carolina’s offensive struggles prevent them from pulling away. A final margin of 10-17 points seems far more realistic than a blowout, making this spread an overreaction to home-field advantage and historical matchups.

Backed by data on form, offensive efficiency, and situational trends, this recommendation represents the most accurate and valuable call for this South Carolina vs Coastal Carolina matchup. The 23.5-point spread overstates the gap between a struggling home offense and a resilient road team with superior recent results. This South Carolina vs Coastal Carolina betting picks analysis strongly supports taking the points with the visitors.

Mason Bennett
Mason Bennett
I’m the voice behind Pick 60 Sports, a long-running U.S. platform built on data-driven analysis and expert picks across the NFL, MLB, NHL, CFL, NBA, soccer, UFC, and tennis. My focus is turning stats into smart, actionable insights for sports fans who bet with strategy.
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