HomeNCAA PicksPenn State VS Nebraska Prediction: November 23, 2025

Penn State VS Nebraska Prediction: November 23, 2025

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Penn State VS Nebraska Preview

The Penn State Nittany Lions host the Nebraska Cornhuskers on November 22, 2025, at 7:00 PM ET at West Shore Home Field at Beaver Stadium in University Park, PA. Penn State enters at 4-6, desperately needing a victory to salvage bowl eligibility, while Nebraska arrives at 7-3 with the nation’s third-ranked pass defense and legitimate postseason aspirations.

This matchup carries significant stakes for both programs, though for vastly different reasons. Penn State must win to extend its season, while Nebraska seeks road momentum heading into the final stretch. The Cornhuskers will start freshman quarterback TJ Lateef in place of injured Dylan Raiola, adding intrigue to an already compelling contest between defensively stout squads.

Our analysis points toward Nebraska covering the 8.5-point spread and the total climbing Over 44.5 points. Both the Penn State VS Nebraska game preview and Penn State VS Nebraska betting odds suggest a tighter contest than the spread indicates, with weather conditions near 38°F and Penn State’s poor recent spread performance creating value on the underdog.

Key Factors for Penn State VS Nebraska

Penn State has covered just 3 of 10 spreads this season, while Nebraska stands 4-5-1 ATS. The Nittany Lions are 3-13 ATS following double-digit wins, precisely their situation after last week’s blowout. Nebraska has lost 15 of its last 18 November road games, but the underdog has covered in 5 of Nebraska’s last 6 contests, highlighting exploitable market tendencies.

Penn State running back Kaytron Allen just posted a career-high 181 rushing yards, indicating the Nittany Lions will lean heavily on the ground game. Nebraska counters with the nation’s third-best pass defense, forcing Penn State into a one-dimensional attack. Freshman TJ Lateef performed admirably in his first start, reducing concerns about the quarterback transition for this Penn State VS Nebraska betting forecast.

Both teams rank top-20 nationally in pass defense, setting up a defensive struggle that favors the underdog. Penn State has won 20 of its last 21 home games against non-ranked opponents, but Nebraska’s elite secondary and desperate bowl positioning create a compelling case for the Cornhuskers to stay within the number in this Penn State VS Nebraska prediction scenario.

Recent Trends for Penn State VS Nebraska

Penn State’s spread struggles define this season, covering at just a 30% clip while consistently disappointing bettors. The Nittany Lions’ 3-13 ATS record after big wins represents a glaring letdown pattern. Meanwhile, Nebraska’s defensive identity has kept the Cornhuskers competitive in nearly every contest, with 5 covers in their last 6 games demonstrating resilience against market expectations.

Home dominance for Penn State against unranked teams creates surface-level confidence, but the underlying metrics tell a different story. The Nittany Lions have struggled to exceed expectations all season, while Nebraska’s road woes in November mask improved overall form. The momentum clearly favors Nebraska entering this critical late-season matchup at Beaver Stadium.

These Penn State VS Nebraska matchup trends reveal systematic inefficiencies in how oddsmakers price both teams. Penn State is overvalued at home, while Nebraska’s situational value as an underdog remains underappreciated. The Penn State VS Nebraska betting insights confirm that backing the Cornhuskers plus the points represents the sharper side of this particular contest.

Our Prediction is Nebraska +8.5 spread, Over 44.5

Nebraska covers the 8.5-point spread based on Penn State’s abysmal post-blowout ATS record and the Cornhuskers’ recent covering streak. Penn State’s inability to exceed inflated home expectations combines with Nebraska’s elite pass defense neutralizing the Nittany Lions’ primary weapon. TJ Lateef’s competent debut reduces quarterback risk, while freezing temperatures favor Nebraska’s defensive identity in this Big Ten clash.

The Over 44.5 hits despite two top-20 pass defenses because Kaytron Allen’s ground dominance and Nebraska’s ability to sustain drives produce enough scoring opportunities. Penn State’s desperation for bowl eligibility forces aggressive playcalling, while Nebraska’s 7-3 record reflects offensive competence under Lateef. Both teams find the end zone multiple times, pushing this total beyond the posted number.

We believe the outcome of the match will be Nebraska +8.5 spread, Over 44.5. Penn State wins outright but fails to cover, likely by a margin between four and seven points. The total clears 44.5 comfortably, with both offenses exceeding modest expectations in a competitive, physical Big Ten battle that validates the underdog position.

This recommendation delivers optimal betting value by exploiting Penn State’s documented spread failures and Nebraska’s underdog covering pattern. Backed by situational trends, defensive matchups favoring the Cornhuskers, and Penn State’s post-win letdown tendency, this represents the sharpest angle for the Penn State VS Nebraska contest. Our Penn State VS Nebraska betting picks maximize value on November 22.

Mason Bennett
Mason Bennett
I’m the voice behind Pick 60 Sports, a long-running U.S. platform built on data-driven analysis and expert picks across the NFL, MLB, NHL, CFL, NBA, soccer, UFC, and tennis. My focus is turning stats into smart, actionable insights for sports fans who bet with strategy.
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