Colorado VS Arizona State Preview
Colorado hosts Arizona State on Saturday, November 22, 2025, at 6:00 PM MST at Folsom Field in Boulder, Colorado. The NCAA matchup pits a struggling Colorado squad (3-7) against a confident Arizona State team (7-3) that enters as a touchdown favorite. Expect a high-scoring affair with Arizona State’s rushing attack exploiting Colorado’s vulnerable run defense.
The betting market has installed Arizona State as a 7-point favorite, with the total set at 48.5 points. Both teams have averaged over 50 combined points in recent contests, suggesting an offensive showcase is likely. No major injuries or lineup changes have been reported as of November 21, meaning both squads will deploy full-strength rosters in this critical late-season encounter.
Early expectations favor the Sun Devils covering the spread while the game sails over the total. This Colorado VS Arizona State game preview examines the tactical mismatches and betting value, with Colorado VS Arizona State betting odds reflecting Arizona State’s superior form and Colorado’s defensive vulnerabilities. The home underdog faces a daunting task against a motivated road favorite hunting momentum heading into the postseason.
Key Factors for Colorado VS Arizona State
Arizona State has won two of the last three meetings, establishing recent dominance in the series. The teams have split ATS outcomes (1-1-1) in head-to-head clashes, but Colorado’s 4-2 ATS home record contrasts sharply with Arizona State’s 2-2 road ATS mark. The Over has hit in two of the last three encounters, with both teams averaging over 50 combined points in home and away settings this season.
Arizona State’s ground game matches up perfectly against Colorado’s porous run defense, creating a critical tactical advantage. The Sun Devils (7-3) bring superior depth and execution, while Colorado (3-7) struggles to contain physical rushing attacks. With no reported injuries or suspensions, Arizona State can exploit this mismatch at full strength, putting immense pressure on Colorado’s vulnerable defensive front throughout the contest.
The Colorado VS Arizona State betting forecast hinges on Arizona State’s ability to control the line of scrimmage and dictate tempo. The Colorado VS Arizona State prediction leans toward the visiting favorites covering the spread while both offenses contribute to a high-scoring affair. Colorado’s home ATS success offers intrigue, but the talent disparity and tactical mismatch favor Arizona State in all key metrics.
Recent Trends for Colorado VS Arizona State
Arizona State enters with momentum, riding superior form into hostile territory. The Sun Devils have demonstrated consistency on both sides of the ball, averaging over 25 points per game while limiting opponents through disciplined execution. Colorado’s 3-7 record reflects systemic issues, particularly on defense where run-stopping failures have plagued the Buffaloes throughout the campaign, costing them critical possessions and field position.
Momentum clearly favors the visitors, who have covered the spread in key road spots this season. Patterns suggest Arizona State thrives when exploiting weak front sevens, exactly the scenario facing Colorado. The turning point in recent meetings has been Arizona State’s ability to establish the run early, controlling clock and wearing down opponents. Colorado’s inability to adjust defensively has cost them in tight contests this year.
The Colorado VS Arizona State matchup trends reveal a high-scoring series with Arizona State ascending. The Colorado VS Arizona State betting insights point to value on the Over given both teams’ offensive capabilities and Colorado’s defensive shortcomings. Arizona State’s recent form and tactical edge suggest they will not only win but cover the touchdown spread comfortably at Folsom Field on Saturday evening.
Our Prediction is Arizona State -7 spread, Over 48.5 total
Arizona State covers the 7-point spread by exploiting Colorado’s weak run defense with a balanced, physical offensive attack. The Sun Devils’ superior depth and execution will prove decisive in the second half as Colorado’s defense fatigues. With no injury concerns limiting either roster, Arizona State’s talent advantage becomes magnified, allowing them to pull away late and secure a comfortable double-digit victory on the road.
The Over 48.5 total represents excellent value given both teams’ offensive firepower and recent scoring trends. Colorado’s defensive struggles guarantee Arizona State scoring opportunities, while the Buffaloes will be forced into a high-tempo passing attack to keep pace. Statistical trends support this outcome, with two of the last three meetings exceeding 50 combined points and both squads averaging explosive offensive outputs in 2025.
We believe the outcome of the match will be Arizona State -7 spread, Over 48.5 total. Arizona State’s rushing attack exploits Colorado’s primary weakness, while the Buffaloes’ inability to control tempo ensures a fast-paced, high-scoring contest. The Sun Devils cover comfortably, winning by 10-plus points in a game that sails over the total, delivering betting value on both markets.
Backed by form analysis, tactical mismatches, and situational trends, this recommendation represents the most accurate and valuable call for this Colorado VS Arizona State matchup. The Sun Devils’ superiority in the trenches and Colorado’s defensive vulnerabilities create a perfect storm for Arizona State bettors. This Colorado VS Arizona State betting picks selection offers strong two-way value in a game where the favorite should dominate while both offenses thrive.
